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Showing 1 to 11 of 11 entries
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Careers of an elite cohort of US basic life science postdoctoral fellows and the influence of their mentor's citation record

postdoctoral

[No authors listed]
GSID: tpROontR6soJ
DG Levitt - BMC medical education, 2010 - bmcmededuc.biomedcentral.com

There is general agreement that the number of US science PhDs being trained far exceeds the number of future academic positions. One suggested approach to this problem is to …

Bioinformatics and the Politics of Innovation in the Life Sciences: Science and the State in the United Kingdom, China, and India.

Science, technology & human values

Salter B, Zhou Y, Datta S, Salter C.
PMID: 27546935
Sci Technol Human Values. 2016 Sep;41(5):793-826. doi: 10.1177/0162243916631022. Epub 2016 Feb 24.

The governments of China, India, and the United Kingdom are unanimous in their belief that bioinformatics should supply the link between basic life sciences research and its translation into health benefits for the population and the economy. Yet at...

Integration and Visualization of Translational Medicine Data for Better Understanding of Human Diseases.

Big data

Satagopam V, Gu W, Eifes S, Gawron P, Ostaszewski M, Gebel S, Barbosa-Silva A, Balling R, Schneider R.
PMID: 27441714
Big Data. 2016 Jun;4(2):97-108. doi: 10.1089/big.2015.0057.

Translational medicine is a domain turning results of basic life science research into new tools and methods in a clinical environment, for example, as new diagnostics or therapies. Nowadays, the process of translation is supported by large amounts of...

Meta-Analytic Methodology for Basic Research: A Practical Guide.

Frontiers in physiology

Mikolajewicz N, Komarova SV.
PMID: 30971933
Front Physiol. 2019 Mar 27;10:203. doi: 10.3389/fphys.2019.00203. eCollection 2019.

Basic life science literature is rich with information, however methodically quantitative attempts to organize this information are rare. Unlike clinical research, where consolidation efforts are facilitated by systematic review and meta-analysis, the basic sciences seldom use such rigorous quantitative...

Modularize and Unite: Toward Creating a Functional Artificial Cell.

Frontiers in molecular biosciences

Wang C, Yang J, Lu Y.
PMID: 34912849
Front Mol Biosci. 2021 Nov 29;8:781986. doi: 10.3389/fmolb.2021.781986. eCollection 2021.

An artificial cell is a simplified model of a living system, bringing breakthroughs into both basic life science and applied research. The bottom-up strategy instructs the construction of an artificial cell from nonliving materials, which could be complicated and...

Single-walled carbon nanotubes as optical probes for bio-sensing and imaging.

Journal of materials chemistry. B

Pan J, Li F, Choi JH.
PMID: 32264414
J Mater Chem B. 2017 Aug 28;5(32):6511-6522. doi: 10.1039/c7tb00748e. Epub 2017 May 08.

The unique physical properties of single-walled carbon nanotubes (SWCNTs) have been exploited in novel applications in various fields including electronics and life sciences. Their photoluminescence in the near-infrared (NIR) range, where optical interference from biological tissues is minimum, has...

GdClean: removal of Gadolinium contamination in mass cytometry data.

Bioinformatics (Oxford, England)

Liu J, Liu L, Qu S, Zhang T, Wang D, Ji Q, Wang T, Shi H, Song K, Fang W, Chen W, Yin W.
PMID: 34320625
Bioinformatics. 2021 Jul 28; doi: 10.1093/bioinformatics/btab537. Epub 2021 Jul 28.

MOTIVATION: Mass cytometry (Cytometry by time-of-flight, CyTOF) is a single-cell technology that is able to quantify multiplex biomarker expressions and is commonly used in basic life science and translational research. However, the widely used Gadolinium (Gd) based contrast agents...

Molecular and cellular mechanisms of mutagenesis. Proceedings of a symposium. April 5-9, 1981, Gatlinburg, Tennessee.

Basic life sciences

[No authors listed]
PMID: 7115265
Basic Life Sci. 1982;20:1-387.

No abstract available.

A Multi-Omics Analysis of PON1 Lactonase Activity in Relation to Human Health and Disease.

Omics : a journal of integrative biology

Petrič B, Kunej T, Bavec A.
PMID: 33306925
OMICS. 2021 Jan;25(1):38-51. doi: 10.1089/omi.2020.0160. Epub 2020 Dec 11.

Paraoxonase 1 (PON1) enzyme has antioxidative properties and is present in mammalian blood and several other body fluids. In blood, PON1 is usually integrated into the high-density lipoprotein (HDL) cholesterol. PON1 is a highly versatile enzyme displaying diverse functions...

Phenotypic screening system using three-dimensional (3D) culture models for natural product screening.

The Journal of antibiotics

Suenaga H, Kagaya N, Kawada M, Tatsuda D, Sato T, Shin-Ya K.
PMID: 34326483
J Antibiot (Tokyo). 2021 Oct;74(10):660-666. doi: 10.1038/s41429-021-00457-8. Epub 2021 Jul 29.

Recent progress in three-dimensional (3D) cell culture systems has attracted much attention in the fields of basic life science and drug development. Newly established methods include 3D co-culture, spheroid culture, and organoid culture; these methods enable more human tissue-like...

Modularize and Unite: Toward Creating a Functional Artificial Cell.

Frontiers in molecular biosciences

Wang C, Yang J, Lu Y.
PMID: 34912849
Front Mol Biosci. 2021 Nov 29;8:781986. doi: 10.3389/fmolb.2021.781986. eCollection 2021.

An artificial cell is a simplified model of a living system, bringing breakthroughs into both basic life science and applied research. The bottom-up strategy instructs the construction of an artificial cell from nonliving materials, which could be complicated and...

Showing 1 to 11 of 11 entries